Mold and Human Health: a Reality Check.
Abstract
There are possibly millions of mold species on earth. The vast majority of these mold spores live in harmony with humans, rarely causing disease. The rare species that does cause disease does so by triggering allergies or asthma, or may be involved in hypersensitivity diseases such as allergic bronchopulmonary aspergillosis or allergic fungal sinusitis. Other hypersensitivity diseases include those related to occupational or domiciliary exposures to certain mold species, as in the case of Pigeon Breeder's disease, Farmer's lung, or humidifier fever. The final proven category of fungal diseases is through infection, as in the case of onchomycosis or coccidiomycosis. These diseases can be treated using anti-fungal agents. Molds and fungi can also be particularly important in infections that occur in immunocompromised patients. Systemic candidiasis does not occur unless the individual is immunodeficient. Previous reports of "toxic mold syndrome" or "toxic black mold" have been shown to be no more than media hype and mass hysteria, partly stemming from the misinterpreted concept of the "sick building syndrome." There is no scientific evidence that exposure to visible black mold in apartments and buildings can lead to the vague and subjective symptoms of memory loss, inability to focus, fatigue, and headaches that were reported by people who erroneously believed that they were suffering from "mycotoxicosis." Similarly, a causal relationship between cases of infant pulmonary hemorrhage and exposure to "black mold" has never been proven. Finally, there is no evidence of a link between autoimmune disease and mold exposure.
Part of Mold & water-damaged buildings research · Curated by Lauren Lowenstein, The Biotoxin Lady
Symptom Clusters
Cited By (2)
- Chloroanisoles and Chlorophenols Explain Mold Odor but Their Impact on the Swedish Population Is Attributed to Dampness and Mold.International journal of environmental research and public health · 2020
- Ten questions concerning occupant health in buildings during normal operations and extreme events including the COVID-19 pandemic.Building and environment · 2021
References (32)
- Dampness in buildings and health (DBH): report from an ongoing epidemiological investigation on the association between indoor environmental factors and health effects among children in SwedenIndoor Air · 2004
- Occurrence of Toxigenic Aspergillus versicolor Isolates and Sterigmatocystin in Carpet Dust from Damp Indoor EnvironmentsApplied and Environmental Microbiology · 2002
- Characterization of Stachybotrys from Water-Damaged Buildings Based on Morphology, Growth, and Metabolite ProductionMycologia · 2002
- Total viable molds and fungal DNA in classrooms and association with respiratory health and pulmonary function of European schoolchildrenPediatric Allergy and Immunology · 2011
- Adverse human health effects associated with molds in the indoor environmentJournal of Occupational and Environmental Medicine · 2003
- Interactions between and can induce apoptosis and cell cycle arrest in mouse RAW264.7 macrophagesToxicology and Applied Pharmacology · 2005
- Intranasal exposure to a damp building mould, Stachybotrys chartarum, induces lung inflammation in mice by satratoxin‐independent mechanismsClinical & Experimental Allergy · 2003
- Fungal fragments in moldy houses: a field study in homes in New Orleans and southern OhioAtmospheric Environment · 2007
- Mycotoxin Adducts on Human Serum Albumin: Biomarkers of Exposure to Stachybotrys chartarumEnvironmental Health Perspectives · 2006
- Relationship between secondary metabolism and fungal developmentMicrobiology and Molecular Biology Reviews · 2002
- Detection of AirborneStachybotrys chartarumMacrocyclic Trichothecene Mycotoxins in the Indoor EnvironmentApplied and Environmental Microbiology · 2005
- Molds and mycotoxins in dust from water-damaged homes in New Orleans after hurricane KatrinaIndoor Air · 2009
- Trichothecene mycotoxins in aerosolized conidia of Stachybotrys atraApplied and Environmental Microbiology · 1987
- Abundant Respirable Ergot Alkaloids from the Common Airborne Fungus Aspergillus fumigatusApplied and Environmental Microbiology · 2005
- The Proportions ofStreptomyces californicusandStachybotrys chartarumin Simultaneous Exposure Affect Inflammatory Responses in Mouse RAW264.7 MacrophagesInhalation Toxicology · 2005
- Specific molds associated with asthma in water-damaged homesJournal of Occupational and Environmental Medicine · 2006
- Mold and endotoxin levels in the aftermath of Hurricane Katrina: a pilot project of homes in New Orleans undergoing renovationEnvironmental Health Perspectives · 2006
- Comparison of inflammatory and cytotoxic lung responses in mice after intratracheal exposure to spores of two different Stachybotrys chartarum strainsToxicological Sciences · 2004
- Synergistic interaction in simultaneous exposure to Streptomyces californicus and Stachybotrys chartarumEnvironmental Health Perspectives · 2004
- Mass Spectrometry-Based Strategy for Direct Detection and Quantification of Some Mycotoxins Produced by Stachybotrys and Aspergillus spp. in Indoor EnvironmentsApplied and Environmental Microbiology · 2007
- Risk from inhaled mycotoxins in indoor office and residential environmentsInternational Journal of Toxicology · 2004
- Acute inhalation toxicity of T-2 mycotoxin in mice*1Fundamental and Applied Toxicology · 1987
- Optimizing a GC-MS method for screening of Stachybotrysmycotoxins in indoor environmentsJournal of Environmental Monitoring · 2007
- Co-cultivation of Streptomyces californicus and Stachybotrys chartarum stimulates the production of cytostatic compound(s) with immunotoxic propertiesToxicology and Applied Pharmacology · 2006
- Effects of microbial cocultivation on inflammatory and cytotoxic potential of sporesInhalation Toxicology · 2005
- mycotoxins and associations with asthmatic symptoms among pupils in schools from Johor BahruPediatric Allergy and Immunology · 2011
- Dampness, bacterial and fungal components in dust in primary schools and respiratory health in schoolchildren across EuropeOccupational and Environmental Medicine · 2014
- Endotoxin, ergosterol, muramic acid and fungal DNA in dust from schools in Johor Bahru, Malaysia--Associations with rhinitis and sick building syndrome (SBS) in junior high school students.The Science of the total environment · 2016
- Rhinitis, Ocular, Throat and Dermal Symptoms, Headache and Tiredness among Students in Schools from Johor Bahru, Malaysia: Associations with Fungal DNA and Mycotoxins in Classroom DustPLoS ONE · 2016
- Chloroanisoles may explain mold odor and represent a major indoor environment problem in Sweden.Indoor air · 2016
- Molecular profiling of fungal communities in moisture damaged buildings before and after remediation - a comparison of culture-dependent and culture-independent methodsBMC Microbiology · 2011
- Respiratory and Allergic Health Effects of Dampness, Mold, and Dampness-Related Agents: A Review of the Epidemiologic EvidenceEnvironmental Health Perspectives · 2011
Related Papers
- Mold inhalation causes innate immune activation, neural, cognitive and emotional dysfunctionBrain Behavior and Immunity · 2020 · 4 shared tags
- THIRTY YEARS OF PUBLISHED RESEARCH ON HUMAN HEALTH EFFECTS OF EXPOSURE TO THE INTERIOR ENVIRONMENT OF WATER-DAMAGED BUILT ENVIRONMENTSMedical Research Archives · 2025 · 4 shared tags
- Dampness and moulds in workplace buildings: Associations with incidence and remission of sick building syndrome (SBS) and biomarkers of inflammation in a 10 year follow-up studyThe Science of The Total Environment · 2012 · 4 shared tags
- Poorly controlled asthma – Easy wins and future prospects for addressing fungal allergyAllergology International · 2023 · 4 shared tags
- Effects of Mycotoxins on Neuropsychiatric Symptoms and Immune ProcessesClinical Therapeutics · 2018 · 4 shared tags
- The Myth of Mycotoxins and Mold InjuryClinical Reviews in Allergy & Immunology · 2019 · 4 shared tags