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From the Th1/Th2 Paradigm towards a Toll-Like Receptor/T-Helper Bias

Netea Mihai G., Van der Meer Jos W. M., Sutmuller Roger P. +2 more2005Antimicrobial Agents and ChemotherapyReview
10.1128/aac.49.10.3991-3996.2005PubMedFree full text
CardiovascularEndocrine (ADH/ACTH/MSH)GastrointestinalHypothalamic-PituitaryImmune/InnateMusculoskeletalNeurologicalOcularRespiratory/Sinus
Bacterial EndotoxinsIndoor Mold (Stachybotrys, Aspergillus, etc.)MycotoxinsVolatile Organic Compounds (VOCs)Water-Damaged Buildings (WDB)

Abstract

Contains fulltext : 47817.pdf (Publisher’s version ) (Open Access)

Key Biomarkers

Alpha Melanocyte Stimulating Hormone (MSH)Immunoglobulin E (IgE)LeptinMatrix Metalloproteinase 9 (MMP9)Vascular Endothelial Growth Factor (VEGF)Visual Contrast Sensitivity (VCS)

Symptom Clusters

Appetite swingsConfusionCoughDifficulty with concentrationExcessive thirstFatigueFrequent urinationHeadacheJoint painLight sensitivityMemory lossMood swingsMuscle achesNight sweatsShortness of breathSinus congestionTingling in extremitiesWord finding difficulty

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  • Bioaerosol Exposure and in vitro Activation of Toll-like Receptors in a Norwegian Waste Sorting PlantSafety and Health at Work · 2021
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    • References (5)

    • TLR4, but not TLR2, mediates IFN-β–induced STAT1α/β-dependent gene expression in macrophagesNature Immunology · 2002
    • Toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: critical role of myeloid differentiation factor 88The Journal of Immunology · 2003
    • Toll-like receptor control of the adaptive immune responsesNature Immunology · 2004
    • Toll-like receptors and innate immunityNature reviews. Immunology · 2001
    • Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cellsJournal of Biological Chemistry · 2001
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