The diagnosis of cognitive impairment associated with exposure to mold
2004Advances in applied microbiologyReview
Hypothalamic-PituitaryImmune/InnateNeurologicalRespiratory/Sinus
Indoor Mold (Stachybotrys, Aspergillus, etc.)MycotoxinsWater-Damaged Buildings (WDB)
Abstract
Key Biomarkers
Abnormal nerve conduction studiesAbnormal QEEG with narrowed frequency bandsAbnormal T, B, and NK cell phenotypesAntinuclear autoantibodies (ANA)Autoantibodies against smooth muscle (ASM)CNS and PNS myelin autoantibodiesElevated autoantibodies to neural antigens (IgA, IgM, IgG)Trichothecene toxins in urine and serum
Symptom Clusters
Autonomic nervous system dysfunctionCognitive impairment (short-term memory loss, concentration deficits, executive dysfunction)Dizziness and vertigoMood disturbances (depression, anxiety)Neurobehavioral dysfunction (balance impairment, reaction time delays, visuospatial deficits)Peripheral neuropathy (numbness, tingling, tremors, muscle weakness)Respiratory symptoms (rhinorrhea, wheezing, airway obstruction)
References (4)
- Building-Associated Pulmonary Disease From Exposure toStachybotrys chartarum and Aspergillus versicolorJournal of Occupational and Environmental Medicine · 1998
- Cognitive impairment associated with toxigenic fungal exposure: a replication and extension of previous findingsApplied Neuropsychology · 2004
- Neuropsychological performance of patients following mold exposureApplied Neuropsychology · 2002
- Toxigenic fungi in a water-damaged building: an intervention studyAmerican Journal of Industrial Medicine · 1998
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