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Base rates of longitudinal RBANS discrepancies at one- and two-year intervals in community-dwelling older adults.

Doyle E Patton, Kevin Duff, Mike R Schoenberg +3 more2005The Clinical NeuropsychologistJournal Article
Endocrine (ADH/ACTH/MSH)Hypothalamic-PituitaryImmune/InnateNeurologicalRespiratory/Sinus

Abstract

Identification of clinically significant change in performance over time on neurocognitive tests is an important aspect of neuropsychological evaluation; however, scant published empirical data exists to guide the clinician in determining the significance of psychometric change across clinically relevant retest intervals. The present study presents base rate data of RBANS score discrepancies in a user-friendly manner based on the performances of a large sample (n=283) of community-dwelling older adults. Data for 1- and 2-year retest intervals are presented in a tabular form that can be used as a convenient reference. Base rates of discrepancy scores were calculated and organized into three groups (i.e., below average, average, and above average) with respect to the participants' OKLAHOMA age- and education-corrected RBANS Total Scale score (Duff, Patton, Schoenberg, Mold, Scott, & Adams, 2003) at initial assessment, in an effort to reduce the influence of regression to the mean and practice effects that is associated with varying levels of cognitive ability. (e.g., Rapport, Axelrod, Theisen, Brines, Kalechstein, & Ricker, 1997; Rapport, Brines, Axelrod, & Theisen, 1997). These data may be helpful in clinical practice by assisting the clinician in determining the clinical significance of score changes.

Part of Mold & water-damaged buildings research, Mycotoxins research · Curated by Lauren Lowenstein, The Biotoxin Lady

Key Biomarkers

Abnormal QEEG findingsAbnormal T and B cell subsetsAntinuclear autoantibodies (ANA)Autoantibodies against CNS/PNS myelinNeural autoantibodiesPeripheral neuropathy on nerve conduction studiesTrichothecene toxin in urine and serum

Symptom Clusters

Autonomic nervous system dysfunctionCognitive decline (visuospatial learning, verbal learning, psychomotor speed)Neurobehavioral dysfunction (balance, reaction time, blink reflex)Neuropsychological impairment (memory, executive function, concentration)Peripheral neuropathy (numbness, tingling, tremors, muscle weakness)Psychological symptoms (depression, anxiety, stress disorders)Respiratory symptoms (rhinorrhea, wheezing, airway obstruction)