Isolation and Identification of Aspergillus fumigatus Mycotoxins on Growth Medium and Some Building Materials
Nieminen SM, Karki R, Auriola S +5 more2002Applied and Environmental MicrobiologyJournal Article
CardiovascularEndocrine (ADH/ACTH/MSH)GastrointestinalHypothalamic-PituitaryImmune/InnateMusculoskeletalNeurologicalOcularRespiratory/Sinus
Bacterial EndotoxinsIndoor Mold (Stachybotrys, Aspergillus, etc.)MycotoxinsVolatile Organic Compounds (VOCs)Water-Damaged Buildings (WDB)
Abstract
Genotoxic and cytotoxic compounds were isolated and purified from the culture medium of an indoor air mold, Aspergillus fumigatus . One of these compounds was identified as gliotoxin, a known fungal secondary metabolite. Growth of A. fumigatus and gliotoxin production on some building materials were also studied. Strong growth of the mold and the presence of gliotoxin were detected on spruce wood, gypsum board, and chipboard under saturation conditions.
Part of Endotoxins research, Mold & water-damaged buildings research, Mycotoxins research, CIRS biomarkers research · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
Symptom Clusters
Appetite swingsConfusionCoughDifficulty with concentrationExcessive thirstFatigueFrequent urinationHeadacheJoint painLight sensitivityMemory lossMood swingsMuscle achesNight sweatsShortness of breathSinus congestionTingling in extremitiesWord finding difficulty
Cited By (6)
- Sick building syndrome (SBS) and exposure to water-damaged buildings: Time series study, clinical trial and mechanismsNeurotoxicology and Teratology · 2006
- Neural autoantibodies and neurophysiologic abnormalities in patients exposed to molds in water-damaged buildingsArchives of Environmental Health An International Journal · 2003
- Can we use indoor fungi as bioindicators of indoor air quality? Historical perspectives and open questionsThe Science of The Total Environment · 2010
- Mycotoxin production by indoor moldsFungal Genetics and Biology · 2003
- Silver-109/Silver/Gold Nanoparticle-Enhanced Target Surface-Assisted Laser Desorption/Ionisation Mass Spectrometry—The New Methods for an Assessment of Mycotoxin Concentration on Building MaterialsToxins · 2021
- Filamentous microorganisms and their fragments in indoor air- a reviewAnnals of agricultural and environmental medicine · 2004
References (5)
- Bacteria, molds, and toxins in water-damaged building materialsApplied and Environmental Microbiology · 1997
- Dampness and airway inflammation and systemic symptoms in office building workersArchives of Environmental Health An International Journal · 1999
- Mycotoxins in crude building materials from water-damaged buildingsApplied and Environmental Microbiology · 2000
- Airborne outbreak of trichothecene toxicosisAtmospheric Environment (1967) · 1986
- Stachybotrys atra Growth and Toxin Production in Some Building Materials and Fodder under Different Relative HumiditiesApplied and Environmental Microbiology · 1994
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