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New agents for the treatment of cancer-related fatigue

Burks TF2001CancerReview
10.1002/1097-0142(20010915)92:6+<1714::aid-cncr1502>3.0.co;2-nPubMedFree full text
CardiovascularEndocrine (ADH/ACTH/MSH)GastrointestinalHypothalamic-PituitaryImmune/InnateMusculoskeletalNeurologicalOcularRespiratory/Sinus
Bacterial EndotoxinsIndoor Mold (Stachybotrys, Aspergillus, etc.)MycotoxinsVolatile Organic Compounds (VOCs)Water-Damaged Buildings (WDB)

Abstract

Existing countermeasures to fatigue, such as exercise, diet, and psychostimulant drugs, are often used but remain unproven in efficacy. Carefully designed trials are necessary to explore the benefits of these and other therapeutic strategies.

Key Biomarkers

Alpha Melanocyte Stimulating Hormone (MSH)Immunoglobulin E (IgE)LeptinMatrix Metalloproteinase 9 (MMP9)Vascular Endothelial Growth Factor (VEGF)Visual Contrast Sensitivity (VCS)

Symptom Clusters

Appetite swingsConfusionCoughDifficulty with concentrationExcessive thirstFatigueFrequent urinationHeadacheJoint painLight sensitivityMemory lossMood swingsMuscle achesNight sweatsShortness of breathSinus congestionTingling in extremitiesWord finding difficulty

Cited By (2)

  • Sick building syndrome (SBS) and exposure to water-damaged buildings: Time series study, clinical trial and mechanismsNeurotoxicology and Teratology · 2006
  • A time-series study of sick building syndrome: chronic, biotoxin-associated illness from exposure to water-damaged buildingsNeurotoxicology and Teratology · 2005

References (1)

  • Molecular Basis of the α‐MSH/IL‐1 AntagonismAnnals of the New York Academy of Sciences · 1999

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