← Explorer/Network

A review of a two-phase population study of multiple chemical sensitivities

Caress SM, Steinemann AC2003Environmental Health PerspectivesReview
10.1289/ehp.5940PubMedFree full text
CardiovascularGastrointestinalNeurologicalRespiratory/Sinus
Volatile Organic Compounds (VOCs)

Abstract

In this review we summarize the findings of a two-phase study of the prevalence, symptomatology, and etiology of multiple chemical sensitivities (MCS). We also explore possible triggers, the potential linkage between MCS and other disorders, and the lifestyle alterations produced by MCS. The first phase of the study consisted of a random sampling of 1,582 individuals from the Atlanta, Georgia, metropolitan area to determine the reported prevalence of a hypersensitivity to common chemicals. In this phase, 12.6% of the sample reported a hypersensitivity. Further questioning of individuals with a hypersensitivity indicated that 13.5% (1.8% of the entire sample) reported losing their jobs because of their hypersensitivity. The second phase was a follow-up questioning of the respondents who initially reported hypersensitivity. In this phase, we found that individuals with hypersensitivity experience a variety of symptoms and triggers. A significant percentage (27.5%) reported that their hypersensitivity was initiated by an exposure to pesticides, whereas an equal percentage (27.5%) attributed it to solvents. Only 1.4% had a history of prior emotional problems, but 37.7% developed these problems after the physical symptoms emerged. This suggests that MCS has a physiologic and not a psychologic etiology.

Symptom Clusters

Chemical hypersensitivityEmotional/psychological problems secondary to physical symptomsJob loss due to hypersensitivityMultiple chemical sensitivities (MCS)

Cited By (4)

  • Multiple Chemical SensitivityOccup Environ Med · 1999
  • Changes in Levels of Nerve Growth Factor in Nasal Secretions after Capsaicin Inhalation in Patients with Airway Symptoms from Scents and ChemicalsEnvironmental Health Perspectives · 2005
  • ACCESS Group HLA and environmental interactions in sarcoidosisSarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2008
  • Multiple chemical sensitivities: reviewCurrent Opinion in Otolaryngology & Head & Neck Surgery · 2007

References (1)

  • Symptomatology and etiology of multiple chemical sensitivities in the southeastern United StatesArchives of Environmental Health An International Journal · 2002

Related Papers

  • 30+ years of knowledge creation: Indoor Air 1991–2021Indoor Air · 2022 · 5 shared tags
  • Synergistic interaction in simultaneous exposure to Streptomyces californicus and Stachybotrys chartarumEnvironmental Health Perspectives · 2004 · 5 shared tags
  • Comparison of inflammatory and cytotoxic lung responses in mice after intratracheal exposure to spores of two different Stachybotrys chartarum strainsToxicological Sciences · 2004 · 5 shared tags
  • Localization of Satratoxin-G in Stachybotrys chartarum Spores and Spore-Impacted Mouse Lung Using ImmunocytochemistryToxicologic Pathology · 2004 · 5 shared tags
  • Correction to “Maitotoxin induces biphasic interleukin-1β secretion and membrane blebbing in murine macrophages”Mol Pharmacol · 2004 · 5 shared tags
  • HUMAN VISUAL FUNCTION IN THE NORTH CAROLINA CLINICAL STUDYON POSSIBLE ESTUARY-ASSOCIATED SYNDROMEJournal of Toxicology and Environmental Health · 2001 ·
5 shared tags