Systems biology of interstitial lung diseases: integration of mRNA and MicroRNA expression changes
Cho J, Gelinas R, Wang K +9 more2011BMC Medical GenomicsJournal Article
Respiratory/Sinus
Abstract
The molecular pathways involved in the interstitial lung diseases (ILDs) are poorly understood. Systems biology dpproaches, witt- global expression dat? sets, were used to identify perturbed gene networks, l o gain sorne onderstanding of the underlying mechanisms, and to develop specific hypotheses rele~~ant Lo these chronic lung di~, pd5es.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
focal adhesion pathwaymicroRNA expression changesmRNA expression changessmooth muscle actin pathwayTGF-β pathwayWnt pathway
Symptom Clusters
Interstitial lung diseasesPulmonary fibrosis
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