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Streptomyces albireticuli lung infection managed as a pulmonary air cyst: a case report and literature review

Jiajiao Liu, Zhaoxia Xu, Yujie Bai +3 more2024Frontiers in Cellular and Infection MicrobiologyReview
10.3389/fcimb.2023.1296491PubMedFree full text
Respiratory/Sinus
Actinomycetes

Abstract

Streptomyces, the largest genus in the Streptomycetaceae family and a prolific producer of antibacterial drugs, is a saprophytic soil organism that rarely causes invasive infections. Here we report a case of necrotic pneumonia caused by Streptomyces albireticuli in a 75-year-old man who presented with progressive chest tightness and dyspnea. Streptomyces albireticuli was isolated from his bronchoalveolar lavage fluid and identified through whole-genome sequencing (WGS) and phylogenetic analysis. The patient responded satisfactorily to clarithromycin therapy. The findings of this study may enhance our vigilance in identifying visceral infections caused by Streptomyces.

Symptom Clusters

Shortness of breath

References (1)

  • Production of proinflammatory mediators by indoor air bacteria and fungal spores in mouse and human cell linesEnvironmental Health Perspectives · 2002

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