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Improving the yield of blood cultures for patients with early Lyme disease

Wormser GP, Nowakowski J, Nadelman RB +3 more1998Journal of Clinical MicrobiologyJournal Article
10.1128/jcm.36.1.296-298.1998PubMedFree full text
DermatologicalImmune/Innate
Lyme & Co-Infections

Abstract

ABSTRACT This study was designed to improve the recovery of Borrelia burgdorferi from blood. With the techniques used, B. burgdorferi could be recovered from the blood of approximately 25% of patients with early Lyme disease associated with erythema migrans. Serum was a better source of culture material than whole blood. The volume of blood cultured correlated directly with yield, particularly for patients with a single erythema migrans lesion.

Cited By (4)

  • Infection with multiple strains of Borrelia burgdorferi sensu stricto in patients with Lyme diseaseArchives of Dermatology · 1999
  • Human Antibody Responses to VlsE Antigenic Variation Protein ofBorrelia burgdorferiJournal of Clinical Microbiology · 1999
  • Four Clones of Borrelia burgdorferi Sensu Stricto Cause Invasive Infection in HumansInfection and Immunity · 1999
  • Genetic Diversity of Borrelia burgdorferi in Lyme Disease Patients as Determined by Culture versus Direct PCR with Clinical SpecimensJournal of Clinical Microbiology · 1999

References (2)

  • Isolation of Borrelia burgdorferi from the blood of seven patients with lyme diseaseThe American Journal of Medicine · 1990
  • The spirochetal etiology of Lyme diseaseNew England Journal of Medicine · 1983

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