Effects of chronic sepsis on contractile properties of fast twitch muscle in an experimental model of critical illness neuromyopathy in the rat
Benoît Rossignol, Gildas Guéret, Jean‐Pierre Pennec +6 more2008Critical Care MedicineJournal Article
Immune/InnateMusculoskeletal
Abstract
Chronic inflammation and sepsis induced a decrease in contractile performances of extensor digitorum longus along with accelerated kinetics of atracurium possibly induced by modified expression of RyR1 receptors and not acetylcholine-receptors.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
Atracurium kineticsRyR1 receptor expression
Symptom Clusters
Critical illness neuromyopathyDecreased muscle contractility
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