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Discrimination of sepsis and systemic inflammatory response syndrome by determination of circulating plasma concentrations of procalcitonin, protein complement 3a, and interleukin-6

O. Selberg, Hartmut Hecker, Michael A. Martin +3 more2000Critical Care MedicineJournal Article
CardiovascularImmune/Innate

Abstract

Our data show that the determination of PCT, IL-6, and C3a is more reliable to differentiate between septic and SIRS patients than the variables CRP and elastase, routinely used at the intensive care unit. The determination of PCT and C3a plasma concentrations appears to be helpful for an early assessment of septic and SIRS patients in intensive care.

Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady

Key Biomarkers

C-reactive proteinComplement 3aElastaseInterleukin-6Procalcitonin

Symptom Clusters

SepsisSystemic Inflammatory Response Syndrome