Sensitivity of sup35 and sup45 suppressor mutants in Saccharomyces cerevisiae to the anti-microtubule drug benomyl
V L Tikhomirova, S G Inge-Vechtomov1996Current GeneticsJournal Article
Respiratory/Sinus
Abstract
SUP35 and SUP45 genes determine the accuracy of translation at the stage of termination. We present indirect evidence indicating that these genes may also control some cellular process mediated by microtubules. A majority of sup35 and sup45 suppressor mutations confer supersensitivity to benomyl, the drug which de-polymerizes microtubules. In addition, data correlating phenotypic manifestations of sup45 suppressor mutations, involving sensitivity to benomyl, respiratory deficiency and a suppressor effect, are also presented.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Related Papers
- Misalignment between Clinical Mold Antigen Extracts and Airborne Molds Found in Water-damaged HomesAnnals of the American Thoracic Society · 2021 · 1 shared tag
- Microbiological Analysis of Indoor Air in Selected Primary Schools: Health Concerns and RecommendationsJournal of Multidisciplinary Science MIKAILALSYS · 2023 · 1 shared tag
- Exposures in the Indoor Environment and Prevalence of Allergic Conditions in the United States of AmericaInternational Journal of Environmental Research and Public Health · 2021 · 1 shared tag
- Dampness, mould, onset and remission of adult respiratory symptoms, asthma and rhinitisEuropean Respiratory Journal · 2019 · 1 shared tag
- Impact of Epidemic Intelligence Service Training in Occupational Respiratory EpidemiologyATS Scholar · 2023 · 1 shared tag
- Streptomyces albireticuli lung infection managed as a pulmonary air cyst: a case report and literature reviewFrontiers in Cellular and Infection Microbiology · 2024 · 1 shared tag