Clinical and serological heterogeneity in patients with anticentromere antibodies
Miyawaki S, Asanuma H, Nishiyama S +1 more2005The Journal of RheumatologyJournal Article
DermatologicalGastrointestinalMusculoskeletalRespiratory/Sinus
Abstract
ACA were positive mostly in patients with SSc with CREST features and partly in other rheumatic disorders. The high levels of ACA may be necessary for the development of CREST features, and frequent concurrence of other disease marker ANA may contribute to the development of heterogeneous clinical characteristics, including overlap syndrome, in patients with ACA.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
Anticentromere Antibodies (ACA)Antinuclear Antibodies (ANA)
Symptom Clusters
CREST featuresRheumatic disease overlap syndromeSjogren's syndrome overlapSystemic Sclerosis
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