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Evaluation of leptin, insulin, orexin, neuropeptide y (NPY) levels in postmortem CSF samples in suicide deaths

Mehmet Tokdemır, Esra Erbak, Ferhat Turgut Tunçez +2 more2025Journal of Affective DisordersJournal Article
10.1016/j.jad.2025.04.015PubMedFree full text
Endocrine (ADH/ACTH/MSH)Hypothalamic-Pituitary

Abstract

While no definitive biomarkers for diagnosing or predicting suicidal behavior exist, this panel of biomarkers could provide valuable insights for developing targeted treatments to manage patients at risk.

Key Biomarkers

Leptin

References (2)

  • The weight of leptin in immunityNature reviews. Immunology · 2004
  • Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistanceAmerican Journal of Physiology-Endocrinology and Metabolism · 2001

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