Pre-pregnancy treatment of semaglutide improves high-fat-diet-induced placental and fetal hypothalamic alterations in a sex-specific manner in rats

Abstract

PpSI improves maternal lipid metabolism before and during pregnancy, and improves placental nutritional transport and fetal hypothalamic appetite-related gene expression, which provides a potential strategy for pre-pregnancy intervention in obese women.

Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady