CIRS Nexus
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Curated by Lauren Lowenstein, The Biotoxin Lady
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CIRS research explorer: 7,510 papers on mold, mycotoxins & biotoxin illness

Peer-reviewed research on Chronic Inflammatory Response Syndrome (CIRS), mapped by body system, environmental trigger (mold, water-damaged buildings, endotoxins, actinobacteria and more) and Shoemaker biomarkers such as C4a, TGF-β1, MSH, VIP and MMP-9. Curated by Lauren Lowenstein, The Biotoxin Lady.

Mold & water-damaged buildingsMycotoxinsActinobacteriaEndotoxinsCyanobacteria & algal bloomsMARCoNSCIRS biomarkersShoemaker ProtocolERMI & HERTSMI-2HLA-DR haplotypesAll topicsBrowse all papers →
7,510 papers in corpus · showing 30

Association between environmental mold exposure and mild cognitive impairment in older adults: a case-control study.

Raquel Rivera-Carvajal, Diana Carolina Tiga-Loza et al.

Frontiers in public health · 2026
DOIDetail
NervousMoldWDB

Herbal Therapeutics for CIRS Biomarkers in Autism Spectrum Disorders: A Mechanistic and Molecular Approach for Neuroimmune Pathology in Pediatrics

Jodie A Dashore, Brian Dashore et al.

Medical Research Archives · 2026
DOIDetail
CardioEndocrineGIHPALyme
Key Biomarkers
ADHC4aMMP-9

More than Glucose Elimination: Additional Benefits of SGLT2 Inhibitors in Glomerular Diseases

Lucia Del Vecchio, Beatriz Fernandez-Fernandez et al.

Drugs · 2026
DOIDetail
EndocrineUrological

Role of microbial volatile compounds (mVOCs) in toxicity from molds-infested buildings: a case report

Shakil A. Saghir, J. S. Bancroft, Rais Ansari

Archives of Clinical Toxicology · 2026
DOIDetail
NervousUrologicalRespiratoryEndotoxinsMoldVOCs

Towards Metabolomics-Guided Healthy and Anti-Aging Nutrition

Petr G. Lokhov, Elena E. Balashova et al.

Metabolites · 2026
DOIDetail
Endocrine

Household environmental characteristics influence the house dust metagenome

Isabella Gamez, Farnaz Fouladi et al.

Environmental Research · 2026
DOIDetail
MoldWDB
Key Biomarkers
Differentially abundant taxa (via ANCOM-BC2)Microbial diversity (alpha diversity measures)

Successful Treatment of Posterior Cortical Atrophy: A Case Report

Kerry Mills Rutland, Neil Nathan et al.

International Journal of Translational Medicine · 2026
DOIDetail
NervousVisual

The role of L-type amino acid transporter 1 in the pathogenicity of Candida albicans

Yibing Lan, Cheng Wu et al.

Microbiology Spectrum · 2026
DOIDetail
EndocrineImmuneMold
Key Biomarkers
TLR2/4

Reducing Indoor Air Pollution as a Strategy for Mitigating Sick Building Syndrome: A Systematic Prisma-Based Review of Intervention Strategies and Health Outcomes

Ekemini Essien, Ekerete Umoh

Research Square · 2026
DOIDetail
RespiratoryWDB

Efficacy of GLP-1 analog peptides, semaglutide, tirzepatide, and retatrutide on MC4R deficient obesity and their comparison

Kosuke Hitaka, Takumi Sugawara et al.

International Journal of Obesity · 2026
DOIDetail
Endocrine

Immunotherapy for Type 2 Diabetes: Mechanisms and Therapeutic Advances

Ravichandran Sanjai, Kunka Mohanram Ramkumar

Scandinavian Journal of Immunology · 2026
DOIDetail
EndocrineImmune
Key Biomarkers
IL-1βIL-6TNF-α

Exploration of hypothalamic disorders of selected indigenous medicinal plants through in-vitro and in-silico approaches

Smrutiranjan Dash, Shweta Singh

Journal of Medicinal Plants Studies · 2026
DOIDetail
EndocrineHPANervousReproductive
Key Biomarkers
ADH

Obesity and type 2 diabetes as chronic inflammation: how does the cytokine evidence align?

Karishma Bhatia, Vikas Kumar Gupta, S. Upadhyay

Frontiers in Endocrinology · 2026
DOIDetail
EndocrineImmune
Key Biomarkers
IL-10IL-1βIL-4

Risks Associated with Dietary Exposure to Contaminants from Foods Obtained from Marine and Fresh Water, Including Aquaculture

Martin Rose

International journal of environmental research and public health · 2026
DOIDetail

Pediatric Neuroimmune and Inflammatory Overlap: Immunopathology of PANS/PANDAS in Autism Spectrum Disorder

Jodie A Dashore, Brian Dashore et al.

Medical Research Archives · 2026
DOIDetail
CardioEndocrineHPAImmune
Key Biomarkers
C4aMMP-9TGF-β1

Dietary β-1,3/1,6-Glucan from Baker’s Yeast Supports Upper Respiratory Mucosal Immune Health in Healthy Adults: Evidence from a Randomized, Double-Blind, Placebo-Controlled Trial

Takashi Kanno, Ken-Ichi Ishibashi et al.

Nutrients · 2026
DOIDetail
ImmuneRespiratory

Multidimensional risk impact of obesity on breast cancer incidence, treatment, and prognosis

Yang Liu, Sunpeng Xu et al.

International Journal of Obesity · 2026
DOIDetail
Endocrine

Asthma and Allergic Bronchopulmonary Aspergillosis: Understanding, Insights, and State-of-the-Art

Puneet Saxena, Valliappan Muthu et al.

Journal of Inflammation Research · 2026
DOIDetail
ImmuneRespiratoryMold
Key Biomarkers
Immunoglobulin E (IgE)

Moderate-to-heavy habitual alcohol use appears to be detrimentally associated with inflammation even when accounting for diet quality in humans: findings from an observational intensive longitudinal study

Kailyn Lowder, Jimikaye B. Courtney

Alcohol and Alcoholism · 2026
DOIDetail
Immune

“Algal-dromes”: a novel conceptual approach to illness in humans exposed to harmful algal bloom toxins

Brett M. Johnson, Mindy L. Richlen et al.

Frontiers in Toxicology · 2026
DOIDetail
CyanoCiguateraOther

PITFALLS OF MYCOTOXIN TESTING: EVIDENCE-BASED FINDINGS CONFIRM MYCOTOXIN ASSAYS USING ANTIBODY TESTING AND URINARY ELISA ARE BASED ON FLAWED SCIENCE

Ritchie C. Shoemaker, Scott McMahon et al.

Medical Research Archives · 2026
DOIDetail
ImmuneUrologicalMoldWDB

A multi-layered approach to elucidate mechanisms of physical function in response to rehabilitation in heart failure with preserved ejection fraction

Andrew Perry, Christopher M. O'Connor et al.

medRxiv · 2026
DOIDetail
CardioEndocrineImmuneMSK

Emodin and the Anthraquinone Scaffold: Therapeutic Promise and Strategies to Overcome Translational Barriers

Rositsa Mihaylova, Viktoria Elincheva et al.

Molecules · 2026
DOIDetail
CardioEndocrineGIImmune
Key Biomarkers
NLRP3 inflammasome

Electrical Stimulation and Its Role in Offsetting the Detrimental Effects of Immobilization After Rotator Cuff Repair in a Rat Model

Meiguang Xu, Lang Bai et al.

The American Journal of Sports Medicine · 2026
DOIDetail
MSK

Cancer cachexia: molecular basis and therapeutic advances

Yuting Tan, Rui Xue et al.

Signal Transduction and Targeted Therapy · 2026
DOIDetail
EndocrineImmune

Diabetes mellitus and risk of multiple sclerosis: a systematic review and meta-analysis

Maoqin Tang, Hongxue Tang et al.

Frontiers in Endocrinology · 2026
DOIDetail
EndocrineImmuneNervous

Comparison of the fungal flora in bedding and floor dust

KAZUHIRO HASHIMOTO

Journal of Microorganism Control · 2026
DOIDetail
Mold

The role of complement and CD4 T cells in preeclampsia and offspring neurodevelopment

Jean F. Regal, Courtney A. O’Kane, Sabrina M. Scroggins

Current Opinion in Physiology · 2026
DOIDetail
CardioImmuneNervousUrological
Key Biomarkers
C3aC5a

Hygrothermal and Climatic Energy Retrofit Strategies for Net-Zero Buildings: Performance Impacts and Occupant Health

Muhammad Kashif, Saif Ul Haq et al.

Sustainability · 2026
DOIDetail
RespiratoryMold

Clearance of multiple antibiotic-resistant coagulase-negative staphylococci is selectively associated with higher circulating α-melanocyte stimulating hormone in patients evaluated for chronic inflammatory response syndrome

Margaret DiTulio, Christian A. Navarro-Torres

Frontiers in Endocrinology · 2026
DOIDetail
EndocrineImmuneRespiratory
Key Biomarkers
MMP-9VIPα-MSH
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