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Benefit from B-Lymphocyte Depletion Using the Anti-CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study

Fluge O, Bruland O, Risa K +7 more2011PLoS ONEJournal Article
10.1371/journal.pone.0026358PubMedFree full text
Immune/InnateNeurological

Abstract

Background: Chronic fatigue syndrome (CFS) is a disease of unknown aetiology. Major CFS symptom relief during cancer chemotherapy in a patient with synchronous CFS and lymphoma spurred a pilot study of B-lymphocyte depletion using the anti-CD20 antibody Rituximab, which demonstrated significant clinical response in three CFS patients.

Cited By (1)

  • Insights into the Complex Biological Network Underlying Myalgic Encephalomyelitis/Chronic Fatigue SyndromeInternational Journal of Molecular Sciences · 2025

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