← Explorer/Network

Clinical features of multiple chemical sensitivity

Levy F1997Brain SciencesReview
10.3390/brainsci14121261PubMedFree full text
Immune/InnateNeurologicalRespiratory/Sinus
Volatile Organic Compounds (VOCs)

Abstract

Multiple chemical sensitivity (MCS) could be called a phenomenon rather than an illness. No single widely accepted test of physiological function can be shown to correlate with the symptoms presented by the patients. In addition to allergy and asthma, patient history can include various "illnesses", and the "diagnosis" is often made by the patient, usually alone or with the help of clinical ecologists. This paper reports the experiences from a department of occupational medicine. More than 80% of the patients were women and solvent exposure was the most common cause of chemical intolerance reported by the patients. Many patients also reported psychosocial stressors. The patients also showed mood disorders with irritability, anxiety, sleep disturbances and depression, often with thoughts centered around different organ symptoms. The symptomatology of MCS is still nonspecific and in no way diagnostic of a specific illness or a medically acceptable syndrome. It may indicate many other conditions, both organic disease and psychopathology.

Symptom Clusters

anxietychemical intolerancedepressionirritabilitymood disordersorgan symptomssleep disturbances

Cited By (1)

  • Mechanisms of multiple chemical sensitivityToxicology Letters · 2002

References (12)

  • Provocative challenges in patients with multiple chemical sensitivityJournal of Allergy and Clinical Immunology · 1997
  • Psychiatric and somatic disorders and multiple chemical sensitivity (MCS) in 264 ‘environmental patients’Psychological Medicine · 2002
  • Hippocampal volume deficits associated with exposure to psychological trauma and posttraumatic stress disorder in adults: a meta-analysisProgress in Neuro-Psychopharmacology and Biological Psychiatry · 2010
  • Evidence for overlap between idiopathic environmental intolerance and somatoform disordersPsychosomatic Medicine · 2005
  • Multiple chemical sensitivities: reviewCurrent Opinion in Otolaryngology & Head & Neck Surgery · 2007

Related Papers

  • Building-Related Illnesses and Mold-Related Conditions2021 · 4 shared tags
  • 30+ years of knowledge creation: Indoor Air 1991–2021Indoor Air · 2022 · 4 shared tags
  • The Sick Building Syndrome as a Part of the Autoimmune (Autoinflammatory) Syndrome Induced by Adjuvant2024 · 4 shared tags
  • Medizinisch klinische Diagnostik bei Schimmelpilzexposition in Innenräumen – Update 2023 (AWMF-Register-Nr. 161/001)Pneumologie · 2024 · 4 shared tags
  • Synergistic interaction in simultaneous exposure to Streptomyces californicus and Stachybotrys chartarumEnvironmental Health Perspectives · 2004 · 4 shared tags
  • Comparison of inflammatory and cytotoxic lung responses in mice after intratracheal exposure to spores of two different Stachybotrys chartarum strainsToxicological Sciences · 2004 · 4 shared tags
Odor processing in multiple chemical sensitivity
Human Brain Mapping · 2007
  • Hippocampal and amygdala volumes in children and adults with childhood maltreatment‐related posttraumatic stress disorder: A meta‐analysisHippocampus · 2008
  • Does dampness and mold in schools affect health? Results of a meta‐analysisIndoor Air · 2019
  • Clinical Characteristics of Disability in Patients with Indoor Air–Related Environmental IntoleranceSafety and Health at Work · 2019
  • Multiple Chemical Sensitivity in Patients Exposed to Moisture Damage at Work and in General Working-Age Population—The SAMDAW StudyInternational Journal of Environmental Research and Public Health · 2021
  • Clinical Findings among Patients with Respiratory Symptoms Related to Moisture Damage Exposure at the Workplace—The SAMDAW StudyHealthcare · 2021
  • Respiratory and Allergic Health Effects of Dampness, Mold, and Dampness-Related Agents: A Review of the Epidemiologic EvidenceEnvironmental Health Perspectives · 2011