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Medical evaluation of Persian Gulf veterans with fatigue and/or chemical sensitivity

Pollet C, Natelson BH, Lange G +8 more1998PubMedJournal Article
PubMed
Endocrine (ADH/ACTH/MSH)Immune/InnateNeurological
Other BiotoxinsVolatile Organic Compounds (VOCs)

Abstract

The purpose of this study was to determine if Gulf War veterans with complaints of severe fatigue and/or chemical sensitivity (n = 72) fulfill case definitions for chronic fatigue syndrome (CFS) and/or multiple chemical sensitivity (MCS) and to compare the characteristics of those veterans who received a diagnosis of CFS (n = 24) to a group of non-veterans diagnosed with CFS (n = 95). Thirty-three veterans received a diagnosis of CFS with 14 having MCS concurrently; an additional six had MCS but did not fulfill a case definition for CFS. The group of fatigued veterans receiving a diagnosis of CFS was comprised of significantly fewer women and fewer Caucasians than the civilian group, and significantly fewer veterans reported a sudden onset to their illness. Veterans with CFS had a milder form of the illness than their civilian counterparts based on medical examiner assessment of the severity of the symptoms, reported days of reduced activity, and ability to work. Since CFS in veterans seems less severe than that seen in civilians, the prognosis for recovery of veterans with this disorder may be better.

Symptom Clusters

Chemical SensitivityFatigue

Cited By (6)

  • Persistence of symptoms in veterans of the first Gulf War: 5-year follow-upEnvironmental Health Perspectives · 2006
  • Controlled exposures to volatile organic compounds in sensitive groupsAnnals of the New York Academy of Sciences · 2001
  • Association of medically unexplained fatigue with ACE insertion/deletion polymorphism in Gulf War veteransMuscle & Nerve · 2004
  • Comorbid illness in women with chronic fatigue syndrome: a test of the single syndrome hypothesisPsychosomatic Medicine · 2003
  • Functioning in individuals with chronic fatigue syndrome: increased impairment with co-occurring multiple chemical sensitivity and fibromyalgiaDynamic Medicine · 2007
  • Chronic fatigue syndrome, fibromyalgia, and multiple chemical sensitivities in a community-based sample of persons with chronic fatigue syndrome-like symptomsPsychosomatic Medicine · 2000

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