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Rate of synthesis of IgG within the blood-brain barrier and the IgG index compared in the diagnosis of multiple sclerosis

Hische E, van der Helm H1987Clinical ChemistryJournal Article
Immune/InnateNeurological

Abstract

Receiver-operating characteristic curves of the IgG synthesis rate and the IgG index show that the IgG index has better discriminating properties with respect to multiple sclerosis. This, added to the fact that the precision of determining the index is much higher than that of the synthesis rate, makes the IgG index the parameter of choice in the diagnosis of multiple sclerosis.

Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady

Key Biomarkers

IgG indexIgG synthesis rate

Symptom Clusters

Multiple sclerosis