Cerebellar abnormalities on proton MR spectroscopy in gluten ataxia
Wilkinson ID, Hadjivassiliou M, Dickson JM +5 more2005Journal of Neurology Neurosurgery & PsychiatryJournal Article
Neurological
Abstract
Gluten sensitivity can manifest with ataxia. The metabolic status of the cerebellum was investigated in 15 patients with gluten ataxia and 10 controls using proton MR spectroscopy. Significant differences were present in mean N-acetyl aspartate levels at short echo time and N-acetyl aspartate/choline ratios at long echo time between the patient and control groups. These data support the hypothesis that cerebellar neuronal physiology differs between patients with gluten ataxia and healthy controls.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
N-acetyl aspartate levelsN-acetyl aspartate/choline ratios
Symptom Clusters
ataxia
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