Demyelinating encephalopathy in Lyme disease
Reik L, Smith L, Khan A +1 more1985NeurologyJournal Article
Immune/InnateNeurological
Lyme & Co-Infections
Abstract
A 38-year-old man from southeastern Connecticut developed a diffuse encephalopathy with partial complex seizures, followed weeks later by arthritis, cryoglobulinemia, and increased serum IgM. CT showed confluent low-density lesions in the deep cerebral white matter consistent with demyelination. Neither the encephalopathy nor the CT abnormalities improved. Lyme disease was diagnosed serologically 4 years later.
Key Biomarkers
CryoglobulinemiaIncreased serum IgMSerological evidence of Lyme disease
Symptom Clusters
ArthritisDemyelinating encephalopathyPartial complex seizuresWhite matter lesions
Cited By (8)
- Inflammatory brain changes in Lyme borreliosisBrain · 1996
- Lyme disease: A neuropsychiatric illnessAmerican Journal of Psychiatry · 1994
- Neurologic abnormalities in Lyme disease without erythema chronicum migransThe American Journal of Medicine · 1986
- Lyme disease: recommendations for diagnosis and treatmentAnnals of Internal Medicine · 1991
- Neurologic manifestations of Lyme disease, the new “Great Imitator”Clinical Infectious Diseases · 1989
- Concurrent neocortical borreliosis and Alzheimer’s diseaseHuman Pathology · 1987
- Acute and chronic neuroborreliosis with and without CNS involvement: a clinical, MRI, and HLA study of 27 casesJournal of Neurology · 1991
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