IL‐1 receptor antagonist in metabolic diseases: Dr Jekyll or Mr Hyde?
Perrier S, Darakhshan F, Hajduch E2006FEBS LettersReview
Endocrine (ADH/ACTH/MSH)Immune/Innate
Abstract
This minireview gets an insight into recent findings on the implication of IL‐1ra and its gene polymorphism in diabetes and obesity, discusses the potential dual effects of IL‐1ra observed in different models, and comments on future directions.
Key Biomarkers
IL-1ra
References (2)
- Leptin deficiency enhances sensitivity to endotoxin-induced lethalityAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1999
- Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosisArteriosclerosis Thrombosis and Vascular Biology · 2000
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