IL‐1 receptor antagonist in metabolic diseases: Dr Jekyll or Mr Hyde?
Perrier S, Darakhshan F, Hajduch E2006FEBS LettersReview
Endocrine (ADH/ACTH/MSH)Immune/Innate
Abstract
This minireview gets an insight into recent findings on the implication of IL‐1ra and its gene polymorphism in diabetes and obesity, discusses the potential dual effects of IL‐1ra observed in different models, and comments on future directions.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
IL-1ra
References (2)
- Leptin deficiency enhances sensitivity to endotoxin-induced lethalityAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1999
- Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosisArteriosclerosis Thrombosis and Vascular Biology · 2000
Related Papers
- Pro-resolving and anti-arthritic properties of the MC1 selective agonist PL8177Frontiers in Immunology · 2022 · 2 shared tags
- CGRP sensory neurons promote tissue healing via neutrophils and macrophagesNature · 2024 · 2 shared tags
- Invited review: Mechanisms of hypophagia during diseaseJournal of Dairy Science · 2021 · 2 shared tags
- Lipid-Induced Insulin Resistance Mechanisms: The Link to Inflammation and Type 2 Diabetes.2021 · 2 shared tags
- Analytical performance of a canine ELISA monocyte chemoattractant protein-1 assay for use in cats and evaluation of circulating levels in normal weight and obese catsActa veterinaria Scandinavica · 2022 · 2 shared tags
- The Relationship Between Insulin Resistance and Cancer in HumansHormone and Metabolic Research · 2025 · 2 shared tags