Genome-wide association study of leprosy

Zhang F; Huang W; Chen S; Sun L; Liu; Li Y; Cui Y; Yan X; Yang H; Yang R; Chu T; Zhang C; Zhang L; Han J; Yu G; Quan C; Yu Y; Zhang Z; Shi B; Cheng H; Wang C; Lin T; Zheng H; Fu X; Zuo X; Wang Q; Long H; Sun Y; Cheng Y; Tian H; Zhou B; Liu H; Lu W; He S; Du W; Shen M; Jin Q; Wang Y; Low H; Erwin T; Yang N; Li J; Zhao X; Jiao Y; Mao L; Yin G; Jiang Z; Wang X; Yu J; Hu Z; Gong C; Liu Y; Liu R; Wang D; Wei D; Liu J; Cao W; Cao H; Yan W; Wei S; Wang K; Hibberd M; Yang S; Zhang X

doi:10.1056/NEJMoa0903753

Genome-wide association study of leprosy

Zhang F, Huang W, Chen S +61 more2009New England Journal of MedicineJournal Article

10.1056/NEJMoa0903753 PubMed Free full text

Abstract

The narrow host range of Mycobacterium leprae and the fact that it is refractory to growth in culture has limited research on and the biologic understanding of leprosy. Host genetic factors are thought to influence susceptibility to infection as well as disease progression.

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