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This paper from the statistical literature looks at measurement of directs effects of treatment on outcome. This paper is more directed at observational studies than on prospective interventional studies

Joffe MM, Colditz GA1998Restriction as a method for reducing bias in the estimation of direct effects. Stat Med

Summary

No abstract is available for this paper. It was published in Restriction as a method for reducing bias in the estimation of direct effects. Stat Med in 1998 by Joffe MM and colleagues.

Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady