Cytokine Expression in the Mouse Brain in Response to Immune Activation by Corynebacterium parvum
Sheng WS, Hu S, Ding JM +2 more2001Clinical and Diagnostic Laboratory ImmunologyJournal Article
Abstract
Cytokine expression in the brain has been suggested to mediate various sickness behaviors. Here we report that intraperitoneal injection of a Corynebacterium parvum antigen in C57BL/6 mice was followed by prolonged upregulation of cytokines in the cerebral cortex and subcortical structures in a time course that coincided with reduced spontaneous running activity.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady