← Explorer/Network

Dissection of a circulating and intrahepatic CD4+Foxp3+ T-cell subpopulation in chronic hepatitis B virus (HBV) infection: A highly informative strategy for distinguishing chronic HBV infection states

Mengjun Zhang, Jijun Zhou, Tingting Zhao +12 more2012The Journal of Infectious DiseasesJournal Article
10.1093/infdis/jis011PubMed
Immune/Innate

Abstract

The delineation of a CD4(+)Foxp3(+) T-cell subpopulation is a highly informative strategy for distinguishing different chronic HBV infection states. HBcAg-derived peptides may be responsible for activation of Tregs that, in turn, specifically inhibit anti-HBV immune response but not liver inflammation.

Key Biomarkers

CD4+Foxp3+ T cellsHBcAg-derived peptidesRegulatory T cells (Tregs)

References (1)

  • Mechanism of T cell hyporesponsiveness to HbcAg is associated with regulatory T cells in chronic hepatitis BWorld Journal of Gastroenterology · 2006

Related Papers

  • Pro-resolving and anti-arthritic properties of the MC1 selective agonist PL8177Frontiers in Immunology · 2022 · 1 shared tag
  • Effects of Omega-3 Polyunsaturated Fatty Acids on the Formation of Adipokines, Cytokines, and Oxylipins in Retroperitoneal Adipose Tissue of MiceInternational Journal of Molecular Sciences · 2024 · 1 shared tag
  • Fungal immunity and pathogenesis in mammals versus the invertebrate model organismGalleria mellonellaPathogens and Disease · 2021 · 1 shared tag
  • TLR signaling pathway and the effects of main immune cells and epigenetics factors on the diagnosis and treatment of infertility and sterilityHeliyon · 2024 · 1 shared tag
  • CGRP sensory neurons promote tissue healing via neutrophils and macrophagesNature · 2024 · 1 shared tag
  • Invited review: Mechanisms of hypophagia during diseaseJournal of Dairy Science · 2021 · 1 shared tag