Dissection of a circulating and intrahepatic CD4+Foxp3+ T-cell subpopulation in chronic hepatitis B virus (HBV) infection: A highly informative strategy for distinguishing chronic HBV infection states
Mengjun Zhang, Jijun Zhou, Tingting Zhao +12 more2012The Journal of Infectious DiseasesJournal Article
Immune/Innate
Abstract
The delineation of a CD4(+)Foxp3(+) T-cell subpopulation is a highly informative strategy for distinguishing different chronic HBV infection states. HBcAg-derived peptides may be responsible for activation of Tregs that, in turn, specifically inhibit anti-HBV immune response but not liver inflammation.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
CD4+Foxp3+ T cellsHBcAg-derived peptidesTregs
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