Changes in mRNA expression of adenosine receptors in human chronic periodontitis
Sun C, Wall N, Angelov N +4 more2011The Chinese journal of dental researchJournal Article
Immune/Innate
Abstract
Inflammation of the gingival tissue is associated with (1) an unchanged expression of A1AR, (2) an increased expression of A2AAR and A2BAR, and (3) a decreased expression of A3AR. Logistic regression analysis indicated that the change in the expression patterns can be used to diagnose/predict periodontitis. This finding indicates that the adenosine receptor expression profile is changed in periodontitis with the potential for future clinical application.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
A1AR expressionA2AAR expressionA2BAR expressionA3AR expressionAdenosine receptor profile
Symptom Clusters
Chronic periodontitisGingival inflammation
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