Neutrophil chloramines: missing links between innate and acquired immunity
Marcinkiewicz J1997Immunology TodayJournal Article
Immune/Innate
Abstract
Neutrophils are the major cellular component of the acute inflammatory response. By contrast, macrophages are the major cellular component in most chronic immunological responses, and act as key regulators of the specific acquired response. Here, Janusz Marcinkiewicz examines recent data indicating that chloramines, the neutrophil-specific products of the myeloperoxidase--hydrogen-peroxide--halide system, may provide a bridge between the afferent branches of the innate and acquired immune response.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
Hydrogen peroxideMyeloperoxidaseNeutrophil chloramines
Symptom Clusters
AsthmaCNS Injury
Related Papers
- Pro-resolving and anti-arthritic properties of the MC1 selective agonist PL8177Frontiers in Immunology · 2022 · 1 shared tag
- Effects of Omega-3 Polyunsaturated Fatty Acids on the Formation of Adipokines, Cytokines, and Oxylipins in Retroperitoneal Adipose Tissue of MiceInternational Journal of Molecular Sciences · 2024 · 1 shared tag
- Fungal immunity and pathogenesis in mammals versus the invertebrate model organismGalleria mellonellaPathogens and Disease · 2021 · 1 shared tag
- TLR signaling pathway and the effects of main immune cells and epigenetics factors on the diagnosis and treatment of infertility and sterilityHeliyon · 2024 · 1 shared tag
- CGRP sensory neurons promote tissue healing via neutrophils and macrophagesNature · 2024 · 1 shared tag
- Invited review: Mechanisms of hypophagia during diseaseJournal of Dairy Science · 2021 · 1 shared tag