Efficacy of voriconazole in a murine model of acute Trypanosoma cruzi infection

Julián Ernesto Nicolás Gulin; Mackenzie A. Eagleson; Miriam Postan; Romina A. Cutrullis; Héctor Freilij; Facundo García‐Bournissen; Patricia B. Petray; Jaime Altcheh

doi:10.1093/jac/dks478

Efficacy of voriconazole in a murine model of acute Trypanosoma cruzi infection

Julián Ernesto Nicolás Gulin, Mackenzie A. Eagleson, Miriam Postan +5 more2012Journal of Antimicrobial ChemotherapyJournal Article

10.1093/jac/dks478 PubMed Free full text

Abstract

Our findings support the potential of voriconazole for the treatment of acute Chagas' disease and motivate future animal studies using varying doses and treatment schemes. Further evaluation of voriconazole for clinical use in human Chagas' patients is warranted.

Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady