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Decreased gray matter volumes in the cingulo-frontal cortex and the amygdala in patients with fibromyalgia

Markus Burgmer, M. Gaubitz, Carsten Konrad +4 more2009Psychosomatic MedicineJournal Article
10.1097/psy.0b013e3181a32da0PubMed
Neurological

Abstract

Our results suggest that structural changes in the pain system are associated with fibromyalgia. As disease factors do not correlate with reduced gray matter volume in areas of the cingulo-frontal cortex and the amygdala in patients, one possible interpretation is that volume reductions might be a precondition for central sensitization in fibromyalgia.

Key Biomarkers

Decreased gray matter volume in amygdalaDecreased gray matter volume in cingulo-frontal cortex

Symptom Clusters

Central sensitizationChronic pain

Cited By (1)

  • Structural brain abnormalities in patients with inflammatory illness acquired following exposure to water-damaged buildings: a volumetric MRI study using NeuroQuantNeurotoxicology and Teratology · 2014

References (1)

  • Striatal grey matter increase in patients suffering from fibromyalgia – A voxel-based morphometry studyPain · 2007

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