Decreased gray matter volumes in the cingulo-frontal cortex and the amygdala in patients with fibromyalgia
Markus Burgmer, M. Gaubitz, Carsten Konrad +4 more2009Psychosomatic MedicineJournal Article
Neurological
Abstract
Our results suggest that structural changes in the pain system are associated with fibromyalgia. As disease factors do not correlate with reduced gray matter volume in areas of the cingulo-frontal cortex and the amygdala in patients, one possible interpretation is that volume reductions might be a precondition for central sensitization in fibromyalgia.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
Decreased gray matter volume in amygdalaDecreased gray matter volume in cingulo-frontal cortex
Symptom Clusters
Central sensitizationChronic pain
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