Occupational eosinophilic bronchitis without asthma due to chloramine exposure
Anna Krakowiak, Wojtek Dudek, U Ruta +1 more2005Occupational MedicineJournal Article
Immune/InnateRespiratory/Sinus
Volatile Organic Compounds (VOCs)
Abstract
A case is discussed of eosinophilic bronchial inflammation without asthma due to chloramine T (CLT) exposure in a nurse. She reported a non-productive chronic cough on contact with CLT during workshifts. She had negative results of skin prick testing to CLT. However, sensitisation to CLT was confirmed by the presence of specific anti-chloramine IgE. Airway responsiveness to histamine was normal before and after CLT challenge. Eosinophil proportion in sputum was increased at 6 and 24 h after CLT challenge.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
Elevated sputum eosinophilsSpecific anti-chloramine IgE
Symptom Clusters
Eosinophilic bronchial inflammationNon-productive chronic cough
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