Factors Characterizing Staphylococcus epidermidis Invasiveness Determined by Comparative Genomics
Yao Y, Sturdevant DE, Villaruz +3 more2005Infection and ImmunityJournal Article
Abstract
ABSTRACT Virulence mechanisms of the leading nosocomial pathogen Staphylococcus epidermidis are poorly understood. We used microarray-based genome-wide comparison of clinical and commensal S. epidermidis strains to identify putative virulence determinants. Our study revealed high genetic variability of the S. epidermidis genome, new markers for invasiveness of S. epidermidis , and potential targets for drug development against S. epidermidis infections.