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Disintegration of Staphylococcus epidermidis Biofilms under Glucose-Limiting Conditions Depends on the Activity of the Alternative Sigma Factor σ B

Jager S, Mack D, Rohde H +2 more2005Applied and Environmental MicrobiologyJournal Article
10.1128/aem.71.9.5577-5581.2005PubMed

Abstract

ABSTRACT To evaluate the role of the polysaccharide intercellular adhesin as an energy-storage molecule, we investigated the effect of nutrient limitation on S. epidermidis biofilms. The stability of established biofilms depends on σ B activity; however, the slow decay of biofilms under conditions of nutrient limitation reveal its use as an energy-storage molecule to be unlikely.

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