Penetration of Rifampin through Staphylococcus epidermidis Biofilms
Zheng Z, Stewart PS2002Antimicrobial Agents and ChemotherapyJournal Article
Abstract
Rifampin penetrated biofilms formed by Staphylococcus epidermidis but failed to effectively kill the bacteria. Penetration was demonstrated by a simple diffusion cell bioassay and by transmission electron microscopic observation of antibiotic-affected cells at the distal edge of the biofilm.
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