Coagulase-negative staphylococcal membrane-damaging toxins, pain intensity, and metabolic changes in temporomandibular disorder patients with chronic muscle pain

McGregor NR, Zerbes M, Niblett SH +4 more2003PubMedJournal Article

Immune/InnateMusculoskeletalNeurological

Abstract

These data suggest that an increased colonization of MDT-CoNS on skin and mucosal membranes was associated with changed proteolysis, increased pain intensity, and an increase in excitatory amino acids consistent with events associated with the development of chronic orofacial muscle pain in TMD patients.

Key Biomarkers

Coagulase-negative staphylococcal membrane-damaging toxinsExcitatory amino acidsProteolysis markers

Symptom Clusters

Chronic muscle painPain intensityTemporomandibular disorder

Cited By (1)

Membrane damaging toxins from couagulase- negative staphylococcus are associated with self-reported temporomandibular disorder (TMD) in patients with chronic fatigue syndromeJournal of Chronic Fatigue Syndrome · 2004