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Successful chemotherapy of transfusion babesiosis

Murray Wittner, KENNETH S. ROWIN, HERBERT B. TANOWITZ +6 more1982Annals of Internal MedicineCase Report
10.7326/0003-4819-96-5-601PubMed
HematologicalImmune/Innate

Abstract

We describe babesiosis transmitted by transfusion. The infected blood donor was identified and a minimum period of infectivity of the donor's blood was established. We report a new modality for chemotherapy consisting of quinine plus clindamycin, and a new endemic focus for this zoonosis on Fire Island, New York. There are insufficient data to establish a reasonably safe period after which visitors and residents of Babesia-endemic foci can become blood donors. Screening of such persons by a rapid serologic test, such as the ELISA or immunofluorescent antibody tests, is suggested.

Key Biomarkers

Serologic antibody tests (ELISA, immunofluorescent antibody)

Cited By (8)

  • Babesiosis in splenectomized adultsThe American Journal of Medicine · 1984
  • When to suspect and how to monitor babesiosisPubMed · 2001
  • Ability of azithromycin in combination with quinine for the elimination of babesial infection in humansAmerican Journal of Tropical Medicine and Hygiene · 1998
  • Coinfecting deer-associated zoonoses: lyme disease, babesiosis and ehrlichiosisClinical Infectious Diseases · 2001
  • Human babesiosis: an emerging tick-borne diseaseInternational Journal for Parasitology · 2000
  • Klempner MS Babesiosis in patients with AID: a chronic infection presenting as fever of unknown originClin Infect Dis · 1996
  • Ecology of Ixodes Dammini-Borne Human Babesiosis and Lyme DiseaseAnnual Review of Entomology · 1985

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References (3)

  • Human Babesiosis on Nantucket IslandAnnals of Internal Medicine · 1977
  • Weisiger RM Babesia microti: pathogenesis of parasite of human origin in the hamsterExp Parasitol · 1975
  • Babesia microti, and Plasmodium berghei yoelii infections in nude miceNature · 1974
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