Simultaneous human granulocytic ehrlichiosis and Lyme borreliosos

Abstract

Letters15 June 1999Recurrent Human Granulocytic Ehrlichiosis and Lyme DiseaseJames R. Johnson, MDJames R. Johnson, MDVeterans Affairs Medical Center; Minneapolis, MN 55417 (Johnson)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-130-12-199906150-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:In their recent report of a patient who developed reinfection with the agent of human granulocytic ehrlichiosis (1), Horowitz and colleagues provided (without discussion) evidence of another interesting phenomenon in the same patient—reinfection with the agent of Lyme disease.The described patient had no detectable serologic response to Borrelia burgdorferi after her initial episode of erythema migrans; this may have been an instance of the much-discussed but little- documented abortive effect of early antimicrobial therapy on the development of an antibody response to the Lyme spirochete. The patient later developed clinical evidence of reinfection, now with seroconversion ...References1. Horowitz HW, Aguero-Rosenfeld M, Dumler SJ, McKenna DF, Hsieh T, Wu J, et al . Reinfection with the agent of human granulocytic ehrlichiosis. Ann Intern Med. 1998;129:461-3. LinkGoogle Scholar2. Guidelines for laboratory evaluation in the diagnosis of Lyme disease. American College of Physicians. Ann Intern Med. 1997; 127:1106-8. Google Scholar3. Rahn DW, Malawista SE. Lyme disease: recommendations for diagnosis and treatment. Ann Intern Med. 1991;114:472-81. LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Veterans Affairs Medical Center; Minneapolis, MN 55417 (Johnson) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoReinfection with the Agent of Human Granulocytic Ehrlichiosis Harold W. Horowitz , Maria Aguero-Rosenfeld , J. Stephen Dumler , Donna F. McKenna , Tze-chen Hsieh , Joseph Wu , Ira Schwartz , and Gary P. Wormser Recurrent Human Granulocytic Ehrlichiosis and Lyme Disease Harold W. Horowitz , Maria E. Aguero-Rosenfeld , and Gary P. Wormser Metrics 15 June 1999Volume 130, Issue 12Page: 1029KeywordsAntibody productionAntimicrobialsBorrelia burgdorferiEhrlichiosisEnzyme linked immunosorbent assayErythemaHumoral immunityLyme diseaseSpirochetesWestern blot Issue Published: 15 June 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...