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Peripheral Th17/Treg imbalance in patients with atherosclerotic cerebral infarction

Li Q, Wang Y, Yu F +6 more2013PubMedJournal Article
PubMedFree full text
CardiovascularImmune/InnateNeurological

Abstract

Th17/Treg cells were imbalanced in ACI patients, and ox-LDL may contribute to this imbalance and lead to the occurrence of ACI suggesting their pathogenetic role in ACI.

Key Biomarkers

ox-LDLTh17 cellsTreg cells

Symptom Clusters

Atherosclerotic cerebral infarctionTh17/Treg imbalance

References (3)

  • Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3The Journal of Experimental Medicine · 2003
  • The Th17/Treg functional imbalance during atherogenesis in ApoE−/− miceCytokine · 2010
  • The role of oxidized low-density lipoprotein in breaking peripheral Th17/Treg balance in patients with acute coronary syndromeBiochemical and Biophysical Research Communications · 2010

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