Anaphylactic reactions to oligosaccharides in red meat: a syndrome in evolution

Saleh H; Embry S; Nauli A; Atyia S; Krishnaswamy G

doi:10.1186/1476-7961-10-5

Anaphylactic reactions to oligosaccharides in red meat: a syndrome in evolution

Saleh H, Embry S, Nauli A +2 more2012Clinical and Molecular AllergyJournal Article

10.1186/1476-7961-10-5 PubMed Free full text

Immune/Innate

Abstract

While most allergic responses to food are directed against protein epitopes and occur within 30 minutes of ingesting the allergen, recent studies suggest that delayed reactions may occur, sometimes mediated by IgE antibodies directed against carbohydrate moieties. The objective of this review is to summarize the clinical features and management of delayed hypersensitivity reactions to mammalian meat mediated by IgE antibodies to galactose-alpha 1,3-galactose (alpha-gal), an oligosaccharide.

Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady

Key Biomarkers

IgE antibodies to galactose-alpha 1,3-galactose (alpha-gal)

Symptom Clusters

Delayed anaphylactic reactions to red meatHypersensitivity reactions

References (3)

The relevance of tick bites to the production of IgE antibodies to the mammalian oligosaccharide galactose-α-1,3-galactoseJournal of Allergy and Clinical Immunology · 2011
STARI, or Masters Disease: Lone Star Tick–Vectored Lyme-like IllnessInfectious Disease Clinics of North America · 2008
Impaired allergy diagnostics among parasite-infected patients caused by IgE antibodies to the carbohydrate epitope galactose-α1,3-galactoseJournal of Allergy and Clinical Immunology · 2011