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Metabolism, molecular hypometabolism and inflammation: Complications of proliferative physiology include metabolic acidosis, pulmonary hypertension, T reg cell deficiency, insulin resistance and neuronal injury

Ritchi C Shoemaker2020Trends in Diabetes and Metabolismarticle
10.15761/tdm.1000118Free full text
CardiovascularEndocrine (ADH/ACTH/MSH)Immune/InnateNeurologicalRespiratory/Sinus

Abstract

brought 435,000 matches, but [disorders of glucose metabolism] had only 177,000 matches. So here is a massive scientific database on metabolism and disorders of metabolism of proteins and sugars, but there is a discrepancy between general versus specific topics in metabolism. Against this dense background of the discussion of the essential elements of metabolism, we have the new transcriptomic findings of "molecular hypometabolism (MHM), " coined by Dr. James Ryan in 2016 describing the simultaneous reduction in the number of copies of ribosomal mRNA and mitoribosomal mRNA made by individuals with a chronic, multisystem, multi-symptom

References (3)

  • Transcriptomic signatures in whole blood of patients who acquire a chronic inflammatory response syndrome (CIRS) following an exposure to the marine toxin ciguatoxinBMC Medical Genomics · 2015
  • Vasoactive intestinal polypeptide (VIP) corrects chronic inflammatory response syndrome (CIRS) acquired following exposure to water-damaged buildingsHealth · 2013
  • Reduction in Forebrain Parenchymal and Cortical Grey Matter Swelling across Treatment Groups in Patients with Inflammatory Illness Acquired Following Exposure to Water-Damaged Buildings2016

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