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Central and peripheral neural circuits regulating glucose homeostasis

Diego Espinoza, Frank Seibold, Sarah A. Stanley2025npj Biomedical Innovations.Review
Endocrine (ADH/ACTH/MSH)

Abstract

Central and peripheral neural circuits are crucial for glucose homeostasis. Technological advances have extended our understanding of the roles of neural circuits in metabolic regulation, potentially allowing the development of novel therapies for glucose control. Here we provide a brief overview of the roles of neural circuits in glucose homeostasis, current therapies for metabolic regulation acting via neural pathways, and opportunities to harness neural circuits as therapies for metabolic diseases.

Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady