Assessing Chemical Intolerance in Parents Predicts the Risk of Autism and ADHD in Their Children
Abstract
High chemical intolerance scores among parents of children with autism, coupled with our 2021 discovery of mast cell activation as a plausible biomechanism for chemical intolerance, suggest that (1) the QEESI can identify individuals at increased risk, (2) environmental counseling may reduce personal exposures and risk, and (3) the global rise in autism and ADHD may be due to fossil-fuel-derived and biogenic toxicants epigenetically "turning on" or "turning off" critical mast cell genes that can be transmitted transgenerationally. It is important to note that this study was observational in nature; as such, further research is needed using controlled trials to confirm causality and explore the proposed mechanism.
References (5)
- What initiates chemical intolerance? Findings from a large population-based survey of U.S. adultsEnvironmental Sciences Europe · 2023
- Chemical Intolerance and Mast Cell Activation: A Suspicious SynchronicityJournal of Xenobiotics · 2023
- A national population study of the prevalence of multiple chemical sensitivityArchives of Environmental Health An International Journal · 2004
- Mast cell activation may explain many cases of chemical intoleranceEnvironmental Sciences Europe · 2021
- Toxicant-induced loss of tolerance for chemicals, foods, and drugs: assessing patterns of exposure behind a global phenomenonEnvironmental Sciences Europe · 2021
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