← Explorer/Network

What effect do mycotoxins, cell wall components, enzymes and other mold components and metabolites have on our health?

Julia Hurraß, Rabea Teubel, Guido Fischer +2 more2024Allergo Journal InternationalJournal Article
10.1007/s40629-024-00295-8Free full text
NeurologicalRespiratory/Sinus
Indoor Mold (Stachybotrys, Aspergillus, etc.)MycotoxinsVolatile Organic Compounds (VOCs)Water-Damaged Buildings (WDB)

Abstract

Abstract The AWMF (Association of the Scientific Medical Societies) mold guideline “Medical clinical diagnostics for indoor mold exposure”—Update 2023 [44] concludes that there is limited or presumed evidence of a link between indoor dampness/mold exposure and health problems. However, there is inadequate or insufficient evidence for an association between indoor dampness/mold exposure and the environmental medical syndromes sick building syndrome (SBS), multiple chemical sensitivity (MCS) and chronic fatigue syndrome (CFS). Newly coined terms, such as biotoxicosis and mold and vapor hypersensitivity syndrome (MDHS) or volatoxins, suggest a nosological specificity of a pathophysiological connection for which, however, there is no evidence to date. The background to this assessment is presented in this paper.

Symptom Clusters

Fatigue

References (23)

  • Fungal Fragments as Indoor Air BiocontaminantsApplied and Environmental Microbiology · 2002
  • Co-occurrence of toxic bacterial and fungal secondary metabolites in moisture-damaged indoor environmentsIndoor Air · 2011
  • Occurrence of Toxigenic Aspergillus versicolor Isolates and Sterigmatocystin in Carpet Dust from Damp Indoor EnvironmentsApplied and Environmental Microbiology · 2002
  • Sick building syndrome (SBS) and exposure to water-damaged buildings: Time series study, clinical trial and mechanismsNeurotoxicology and Teratology · 2006
  • Effects of toxic exposure to molds and mycotoxins in building-related illnessesArchives of Environmental Health An International Journal · 2003
  • A time-series study of sick building syndrome: chronic, biotoxin-associated illness from exposure to water-damaged buildingsNeurotoxicology and Teratology · 2005
  • Stachybotrys chartarum, Trichothecene Mycotoxins, and Damp Building–Related Illness: New Insights into a Public Health Enigma

Related Papers

  • 30+ years of knowledge creation: Indoor Air 1991–2021Indoor Air · 2022 · 6 shared tags
  • Medizinisch klinische Diagnostik bei Schimmelpilzexposition in Innenräumen – Update 2023 (AWMF-Register-Nr. 161/001)Pneumologie · 2024 · 6 shared tags
  • Synergistic interaction in simultaneous exposure to Streptomyces californicus and Stachybotrys chartarumEnvironmental Health Perspectives · 2004 · 6 shared tags
  • Comparison of inflammatory and cytotoxic lung responses in mice after intratracheal exposure to spores of two different Stachybotrys chartarum strainsToxicological Sciences · 2004 · 6 shared tags
  • Localization of Satratoxin-G in Stachybotrys chartarum Spores and Spore-Impacted Mouse Lung Using ImmunocytochemistryToxicologic Pathology · 2004 · 6 shared tags
  • Correction to “Maitotoxin induces biphasic interleukin-1β secretion and membrane blebbing in murine macrophages”Mol Pharmacol · 2004 · 6 shared tags
Toxicological Sciences · 2008
  • Use of surrogate markers of biological agents in air and settled dust samples to evaluate a water-damaged hospitalIndoor Air · 2005
  • Bacterial strains from moldy buildings are highly potent inducers of inflammatory and cytotoxic effectsIndoor Air · 2005
  • Molds and mycotoxins in dust from water-damaged homes in New Orleans after hurricane KatrinaIndoor Air · 2009
  • Exposure assessment of residential mould, fungi and microbial components in relation to children’s health: Achievements and challengesInternational Journal of Hygiene and Environmental Health · 2013
  • Correlation between the prevalence of certain fungi and sick building syndromeOccupational and Environmental Medicine · 1998
  • Fungal and endotoxin measurements in dust associated with respiratory symptoms in a water-damaged office buildingIndoor Air · 2006
  • Sick Building Syndrome. III.Stachybotrys chartarumJournal of Asthma · 2000
  • Toxicant-induced loss of tolerance for chemicals, foods, and drugs: assessing patterns of exposure behind a global phenomenonEnvironmental Sciences Europe · 2021
  • The role of Stachybotrys mycotoxins in building-related illnessAmerican Industrial Hygiene Association Journal · 2001
  • Molds in floor dust and building-related symptoms among adolescent school children: a problem for boys only?Indoor Air · 2005
  • Moist and Mold Exposure is Associated With High Prevalence of Neurological Symptoms and MCS in a Finnish Hospital Workers CohortSafety and Health at Work · 2020
  • SBS symptoms in relation to dampness and ventilation in inspected single-family houses in SwedenInternational Archives of Occupational and Environmental Health · 2017
  • Dampness and moulds in workplace buildings: Associations with incidence and remission of sick building syndrome (SBS) and biomarkers of inflammation in a 10 year follow-up studyThe Science of The Total Environment · 2012
  • Clinical Characteristics of Disability in Patients with Indoor Air–Related Environmental IntoleranceSafety and Health at Work · 2019
  • Association between indoor microbiome exposure and sick building syndrome (SBS) in junior high schools of Johor Bahru, MalaysiaThe Science of The Total Environment · 2021
  • Onset of mucosal, dermal, and general symptoms in relation to biomarkers and exposures in the dwelling: a cohort study from 1992 to 2002Indoor Air · 2012