Analysis of Salivary Neuropeptides in Anxiety and Depression Using the Luminex MAGPIX® System
Ida Kupcová, Ľuboš Danišovič, Sona Bernatova +1 more2024CureusJournal Article
Hypothalamic-PituitaryNeurological
Abstract
The results of this study indicate that the levels of the studied salivary neuropeptides, OXT, alpha-MSH, beta-endorphin, neurotensin, and substance P, are statistically significantly reduced in individuals with depression compared to healthy controls.
Key Biomarkers
Alpha Melanocyte Stimulating Hormone (MSH)
Symptom Clusters
AnxietyDepression
References (3)
- α-Melanocyte-Stimulating Hormone and Related Tripeptides: Biochemistry, Antiinflammatory and Protective Effects in Vitro and in Vivo, and Future Perspectives for the Treatment of Immune-Mediated Inflammatory DiseasesEndocrine Reviews
- Decreased plasma neuropeptides in first-episode schizophrenia, bipolar disorder, major depressive disorder: associations with clinical symptoms and cognitive functionFrontiers in Psychiatry · 2023
- α-MSH-catabolic enzyme prolylcarboxypeptidase in nucleus accumbens shell ameliorates stress susceptibility in mice through regulating synaptic plasticityActa Pharmacologica Sinica · 2023
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