Skeletal muscle-secreted myokine interleukin-6 induces white adipose tissue conversion into beige adipose tissue in myostatin gene knockout pigs
Mei‐Fu Xuan, Zhao‐Bo Luo, Sheng‐Zhong Han +10 more2021Domestic Animal EndocrinologyJournal Article
Immune/InnateMusculoskeletal
Abstract
Myostatin (MSTN) is primarily expressed in skeletal muscle and plays an important role in the regulation of muscle growth and development as well as fat deposition; however, little is known about the molecular mechanism through which MSTN regulates body fat deposition. Therefore, in this study, we sought to identify the signaling pathways through which MSTN regulates fat accumulation in pigs. MSTN knockout (MSTN
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
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