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The causal effect of adipose tissue on Hodgkin’s lymphoma: two-sample Mendelian randomization study and validation

Lihua Wu, Fei Liao, Xiangli Guo +1 more2024Frontiers in ImmunologyJournal Article
10.3389/fimmu.2024.1400756PubMedFree full text
Endocrine (ADH/ACTH/MSH)Hematological

Abstract

The MR analysis study demonstrated a direct correlation between lower BMI and HL. This suggested that a decrease in adipose tissue increases the risk of developing HL. Nevertheless, further research is essential to grasp the underlying mechanism of this causal association comprehensively.

References (1)

  • Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistanceAmerican Journal of Physiology-Endocrinology and Metabolism · 2001

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