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BAO-Ag-NPs as Promising Suppressor of ET-1/ICAM-1/VCAM-1Signaling Pathway in ISO-induced AMI in Rats

Yasser O. Mosaad, Hayam Ateyya, Mohammed A. Hussein +4 more2023Current Pharmaceutical BiotechnologyJournal Article
10.2174/0113892010256434231010062233PubMed
Immune/Innate

Abstract

BAO-Ag-NPs protect against AMI in vivo by regulating inflammation, excessive autophagy, and oxidative stress, as well as lowering apoptosis via suppression of the ET-1, ICAM-1, and VCAM-1 signaling pathways.

Symptom Clusters

Oxidative stress

References (1)

  • TNF-alpha reduces cerebral blood volume and disrupts tissue homeostasis via an endothelin- and TNFR2-dependent pathwayBrain · 2002

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