CXCL10highTNFαhighKi67+ Microglia Recruit and Activate CD8+ T Cells in the Brainstem During Experimental Cerebral Malaria
Yi Wang, Jiao Liang, Chao Yang +11 more2025CNS Neuroscience & TherapeuticsJournal Article
Immune/InnateNeurological
Abstract
Our study identified an ECM-associated microglia subtype and explored its interaction with CD8+ T cells, which deepened the understanding of the multifaceted role of microglia in the pathogenesis of CM neuroinflammation.
Part of CIRS Nexus · Curated by Lauren Lowenstein, The Biotoxin Lady
Key Biomarkers
TNF-α
Symptom Clusters
Neuroinflammation
Related Papers
- CGRP sensory neurons promote tissue healing via neutrophils and macrophagesNature · 2024 · 2 shared tags
- Invited review: Mechanisms of hypophagia during diseaseJournal of Dairy Science · 2021 · 2 shared tags
- Diabetic complications and prospective immunotherapyFrontiers in Immunology · 2023 · 2 shared tags
- Gut-Brain Inflammation Due to Toxin-Activated Mast Cells and Microglia in Autism Spectrum DisorderPreprints.org · 2025 · 2 shared tags
- The Role of Adipokines and Myokines in the Pathogenesis of Different Obesity Phenotypes—New PerspectivesAntioxidants · 2023 · 2 shared tags
- Herbal Therapeutics for CIRS Biomarkers in Autism Spectrum Disorders: A Mechanistic and Molecular Approach for Neuroimmune Pathology in PediatricsMedical Research Archives · 2026 · 2 shared tags